Abstract Multi-omics profiling by CITE-seq bridges the RNA-protein gap in single-cell analysis but has been largely applied to liquid biopsies.Applying CITE-seq to clinically relevant solid biopsies to characterize healthy tissue and the tumor microenvironment is an essential next step in single-cell translational studies.In this study, gating of c
In this study, the aim was to evaluate the impact of Tai Ji on perceived quality of life (QoL).To this end, an anonymous online questionnaire was designed, compatible with the guidelines Lemon Reamer of the WHO for the definition of QoL, on the Microsoft Forms platform, using multiple-choice questions, short text answers, Baby Bottles and Likert-ba
Neuroinflammation is an important factor in the pathogenesis of neurodegenerative diseases.Microglia-derived lysosomal cathepsins have been increasingly recognized as important inflammatory mediators that trigger signaling pathways that aggravate neuroinflammation.In vitro, a contribution to neuroinflammation processes has been shown for cathepsin
Currently, due to the high costs of production and expensive raw materials, approaches, including, making models smaller and lighter, are especially considered in the design Bamboo of structures.In order to better describe the capabilities, efficiency, and limitations of an innovative field called topology optimization, various practical problems u
Persistent immune activation is a striking consequence of HIV-1 infection and a driving force of CD4+ T cell depletion and AIDS events during chronic infection.High level of T cell immune activation associates with antiretroviral therapy (ART)-treated clinical outcomes in chronically HIV-1-infected patients.However, the role of T cell activation du